The success of the controlled ovarian hyperstimulation (COH) protocols is based mostly on the response of the ovaries during the external administration of gonadotropins, primarily with external FSH; this response may vary a lot in women and the objective of pharmacogenetics is to optimize the procedures for the in vitro fertilization (IVF). The medical experience [...]

Over the last years many scientific studies on the relation between the FSH receptor (FSHR) and the risk of a non-physiological spermatogenesis have been published. These studies have underlined how the presence of allelic variants in the encoding gene for the FSHR can be related to a functional deficit in the spermatogenesis process and therefore [...]

<!– @page { margin: 0.79in } P { margin-bottom: 0.08in } –> WARFARIN Warfarin is an anticoagulant used in the prevention of thrombosis. Its pharmacological action and its effectiveness is widely documented but also its important collateral effects, like the risk of serious hemorrhages; beside that the anticoagulant therapy with warfarin can increase the risk [...]